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LIX/CXCL6 (92 aa)

CAT: 0209-M10-114Size: 20 µgDry Ice: NoHazardous: No
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CAT#:0209-M10-114Size:20 µg
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Description
LIX is a CXC chemokine that signals through the CXCR2 receptor. It is expressed in monocytes, platelets, endothelial cells, and mast cells. LIX is a chemoattractant for neutrophils. The two naturally occurring variants of LIX; LIX 1-78 (GCP-2) and LIX 9-78 (GCP-2), contain 78 and 70 amino acid residues, respectively. LIX contains the four conserved cysteine residues present in CXC chemokines, and also contains the ‘ELR’ motif common to CXC chemokine that bind to the CXCR1 and CXCR2 receptors. Recombinant murine LIX is a 9.8 kDa protein containing 93 amino acid residues.
Synonyms
Cxcl5; LIX; GCP-2; Scyb5; Scyb6; ENA-78; AMCF-II
NCBI Gene ID
20311
UniProt
P50228
Accession Number
NP_033167.2
Accession Number mRNA
NM_009141.2
Chromosomal Location
5 E1; 5 53.0 cM
Reactivity
Mouse
Cross Reactivity
Human, Mouse
Sequence
APSSVIAATE LRCVCLTVTP KINPKLIANL EVIPAGPQCP TVEVIAKLKN QKEVCLDPEA PVIKKIIIQK ILGSDKKKAK RNALAVERTA SVQ
Endotoxin
< 0.1 ng/µg of protein (< 1EU/µg)
Purity
> 98% by SDS-PAGE & HPLC analyses
Bioactivity
Determined by its ability to chemoattract human neutrophils using a concentration range of 10-100 ng/ml.
Length
93
Form
Lyophilized
Molecular Weight
9.8 kDa
Host or Source
E. coli

UniProtKB · P50228

C-X-C motif chemokine 5

CXCL5_MOUSE · Mus musculus

View on UniProt ↗
Primary accession
P50228
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
Cxcl5
Protein existence
1: Evidence at protein level
Organism
Mus musculus (Mouse)
Taxonomy ID
10090
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
Q8K3I3
Protein keywords

Biological process

ChemotaxisInflammatory response

Molecular function

Cytokine

Technical term

Direct protein sequencingReference proteome

PTM

Disulfide bond

Cellular component

Secreted

Domain

Signal

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Alternative Products

CatalogName
P1293-5LIX (CXCL6), Murine Recombinant
L2526-01ALipopolysaccharide-induced CXC Chemokine (LIX, CXCL6)
PROTP50228-2Recombinant Murine LIX (CXCL6) [70a.a.] Protein
PP1212B2LIX (CXCL6) rabbit polyclonal antibody, Biotin
PROTP50228-3Recombinant Murine LIX (CXCL6) [93a.a] Protein
PP1212P2LIX (CXCL6) rabbit polyclonal antibody, Aff - Purified
MBS697406-01Murine LIX (CXCL6) Pre-Coated ELISA Kit
L2526-02-01Lipopolysaccharide-induced CXC Chemokine (LIX, CXCL6) (Biotin)
70R-LR013LIX antibody
PT-A03359-01LIX Mouse

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