LIX

• Description:

  Mouse LIX (LPS-induced CXC chemokine) protein sequence is identical to a previously identified mouse neutrophil chemotactic protein (designated mouse GCP-2) that is produced by stimulated mouse epithelial cells and fibroblasts. Among human CXC chemokines, mouse LIX is most closely related to the two highly homologous human neutrophil chemoattractants GCP-2/CXCL6 and ENA-78/CXCL5. Mouse LIX differs from these two human proteins by having an extended C-terminus. The first 78 amino acid residues within the predicted mature mouse LIX share approximately 61% and 55% amino acid sequence identity with human GCP-2 and ENA-78, respectively.

• Synonyms:

  Cxcl5; LIX; GCP-2; Scyb5; Scyb6; ENA-78; AMCF-II

• NCBI Gene ID:

  20311

• UniProt:

  P50228

• Accession Number:

  NP_033167.2

• Accession Number mRNA:

  NM_009141.2

• Chromosomal Location:

  5 E1; 5 53.0 cM

• Reactivity:

  Anti-Mouse

• Cross Reactivity:

  Mouse

• Target Antigen:

  Recombinant mouse LIX

• Clone:

  (#4F47)

• Applications:

  WB, N

• Purification Method:

  Protein A/G chromatography

• Assay Protocol:

  Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

• Form:

  Lyophilized

• Buffer:

  PBS

• Reconstitution:

  PBS

• Storage Conditions:

  Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.

• Host or Source:

  Rat

• Isotype:

  IgG2