LEC/NCC-4 (CCL16) Recombinant Protein

LEC/NCC-4 (CCL16) Recombinant Protein

• Description: LEC is a CC chemokine that can signal through the CCR8 and CCR1 receptors. It is expressed in the liver, spleen, and thymus. LEC is chemotactic towards monocytes and lymphocytes but not neutrophils. Recombinant human LEC is an 11.2 kDa protein containing 97 amino acid residues, including the four conserved cysteine residues present in CC chemokines.
• Synonyms: CCL16; LEC; LMC; NCC4; CKb12; HCC-4; LCC-1; Mtn-1; NCC-4; SCYL4; ILINCK; SCYA16
• CAS Number: 9000-83-3
• NCBI Gene ID: 6360
• UniProt: O15467
• Accession Number: NP_004581.1
• Accession Number mRNA: NM_004590.2
• Gene Location: 17q11.2
• Host: E. coli
• Origin Species: Human
• Species Reactivity: Mouse, Human, Bacteria
• Sequence: QPKVPEWVNT PSTCCLKYYE KVLPRRLVVG YRKALNCHLP AIIFVTKRNR EVCTNPNDDW VQEYIKDPNL PLLPTRNLST VKIITAKNGQ PQLLNSQ
• Detection Range: Determined by its ability to chemoattract total human monocytes using a concentration range of 10-100 ng/ml.
• Endotoxin: < 0.1 ng/µg of protein (<1EU/µg)
• Purity: > 98% by SDS-PAGE & HPLC analyses
• Length: 97
• Form: Lyophilized
• Molecular Weight: 11.2 kDa
• Shipping Conditions: Room Temperature