IL-4 Recombinant Protein

IL-4 Recombinant Protein

• Description: Interleukin 4 (IL-4) is a pleiotropic cytokine produced by activated T cells, mast cells, and basophils. It was initially identified as a B cell differentiation factor (BCDF), as well as a B cell stimulatory factor (BSF1). IL-4 has since been shown to have multiple biological effects on hematopoietic and non-hematopoietic cells, including B and T cells, monocytes, macrophages, mast cells, myeloid and erythroid progenitors, fibroblasts, and endothelial cells. Rat, mouse and human IL-4 are species-specific in their activities.
• Synonyms: Il4; Il4e12
• CAS Number: 9000-83-3
• NCBI Gene ID: 287287
• UniProt: P20096
• Accession Number: NP_958427
• Accession Number mRNA: NM_201270
• Gene Location: 10q22
• Host: E. coli
• Origin Species: Rat
• Species Reactivity: Mouse, Rat, Human
• Sequence: MHGCNDSPLR EIINTLNQVT EKGTPCTEMF VPDVLTATRN TTENELICRA SRVLRKFYFP RDVPPCLKNK SGVLGELRKL CRGVSGLNSL RSCTVNESTL TTLKDFLESL KSILRGKYLQ SCTSMS
• Detection Range: Tested by its ability to suppress LPS-induced TNF-α and MIP-2 production in mouse splenocytes.
• Endotoxin: < 0.1 ng/µg of protein (<1EU/µg)
• Purity: > 98% by SDS-PAGE & HPLC analyses
• Length: 126
• Form: Lyophilized
• Molecular Weight: 14 kDa
• Shipping Conditions: Room Temperature