Lactogen, placental

• Description:

  Recombinant human placental lactogen, one polypeptide chain containing 199 amino and an additional Ala at N-terminus acids and having a molecular mass of ~ 22.4 kDa, was purified by proprietary chromatographic techniques.

• Synonyms:

  Chorionic somatomammotropin hormone 1, Choriomammotropin, Placental lactogen (PL)

• NCBI Gene ID:

  1442

• UniProt:

  P0DML2

• Accession Number:

  NP_001308.1

• Accession Number mRNA:

  NM_001317.6

• Reactivity:

  Human

• Cross Reactivity:

  Human

• Sequence:

  AVQTVPLSRLFDHAMLQAHRAHQLAIDTYQEFEETYIPKDQKYSFLHDSQTSFCFSDSIPTPSNMEETQQKSNLELLRISLLLIESWLEPVRFLRSMFANNLVYDTSDSDDYHLLKDLEEGIQTLMGRLEDGSRRTGQILKQTYSKFDTNSHNHDALLKNYGLLYCFRKDMDKVETFLRMVQCRSVEGSCGF

• Assay Protocol:

  It is recommended to reconstitute the lyophilized hPL in sterile water or 0.4% NaHCO3 adjusted tp pH 8-9, not less than 100µg/ml, which can then be further diluted to other aqueous solutions, preferably in presence of carrier protein.

• Endotoxin:

  < 0.1 ng/µg of protein (< 1EU/µg)

• Purity:

  > 98.0% as determined by Gel filtration and SDS-PAGE gel.

• Bioactivity:

  Recombinant human PL is fully biologically active as evidenced by inducing proliferation of Nb2 cells.

• Length:

  192

• Form:

  Lyophilized

• Reconstitution:

  Water

• Molecular Weight:

  22.4 kDa

• Host or Source:

  E. coli

• N Terminal Sequence:

  AVQTVP