KC (CXCL1)

CAT: 0209-M10-027SSize: 5 µgDry Ice: NoHazardous: No
CAT#:0209-M10-027SSize:5 µg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
All three isoforms of GRO or KC are CXC chemokines that can signal through the CXCR1 or CXCR2 receptors. The GRO proteins chemoattract and activate neutrophils and basophils. Recombinant murine KC is a 7.8 kDa protein consisting of 72 amino acids including the 'ELR' motif common to the CXC chemokine family that bind to CXCR1 or CXCR2.
Synonyms
CXCL1
NCBI Gene ID
14825
UniProt
P12850
Accession Number
NP_032202.1
Accession Number mRNA
NM_008176.3
Chromosomal Location
5 E-F; 5 51.0 cM
Reactivity
Mouse
Cross Reactivity
Human, Rat, Mouse
Sequence
APIANELRCQ CLQTMAGIHL KNIQSLKVLP SGPHCTQTEV IATLKNGREA CLDPEAPLVQ KIVQKMLKGV PK
Endotoxin
< 0.1 ng/µg of protein (< 1EU/µg)
Purity
> 98% by SDS-PAGE & HPLC analyses
Bioactivity
Determined by its ability to chemoattract total human neutrophil population using a concentration range of 10.0-100.0 ng/ml.
Length
72
Form
Lyophilized
Molecular Weight
7.8 kDa
Host or Source
E. coli

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