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JE (MCP-1, CCL2)

CAT: 0209-103-P22Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0209-103-P22Size:100 µg
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Description
JE or MCP-1, also known as monocyte chemotactic and activating factor (MCAF), was initially purified based on its ability to chemoattract monocytes. Subsequent to its cloning and sequencing, it became evident that this protein is also identical to the product of the human JE gene. The JE gene, originally identified in mouse fibroblasts, is a platelet-derived growth factor (PDGF) -inducible gene.
Synonyms
Ccl2; JE; HC11; MCAF; MCP1; MCP-1; Scya2; Sigje; SMC-CF; AI323594
NCBI Gene ID
20296
UniProt
P10148
Accession Number
NP_035463.1
Accession Number mRNA
NM_011333.3
Chromosomal Location
17q11.2-q12
Reactivity
Anti-Mouse
Cross Reactivity
Mouse
Target Antigen
Recombinant mouse JE (MCP-1)
Clone
Rabbit IgG
Applications
ELISA, WB, N
Purification Method
Antigen-affinity purified
Assay Protocol
Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.
Form
Lyophilized from PBS
Buffer
PBS
Reconstitution
Water
Storage Conditions
The lyophilized antibody is stable for at least 2 years from date of receipt at -20°C. The reconstituted antibody is stable for at least two weeks at 2-8°C. Frozen aliquots are stable for at least 6 months when stored at -20°C.
Host or Source
Rabbit

UniProtKB · P10148

C-C motif chemokine 2

CCL2_MOUSE · Mus musculus

View on UniProt ↗
Primary accession
P10148
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
Ccl2
Protein existence
1: Evidence at protein level
Organism
Mus musculus (Mouse)
Taxonomy ID
10090
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
Q9QYD7
Protein keywords

Biological process

ChemotaxisInflammatory response

Molecular function

Cytokine

Technical term

Direct protein sequencingReference proteome

PTM

Disulfide bondGlycoproteinPyrrolidone carboxylic acid

Cellular component

Secreted

Domain

Signal