IL-31

• Description :

  Interleukin 31 (IL-31) is a secreted, T-cell-derived, 24- kDa, short-chain member of the alpha-helical family of cytokines. The mature region is 141 amino acids (aa) in length and exhibits four alpha-helices. Human and mouse IL-31 are highly divergent at 24% aa sequence identity. The receptor for IL-31 is found on keratinocytes and monocytes. It is a heterodimer composed of the Oncostatin M receptor and a novel gp130-related molecule. IL-31 may be involved in pruritis, or skin itching.

• Synonyms :

  IL31; IL-31

• NCBI Gene ID :

  386653

• UniProt :

  Q6EBC2

• Accession Number :

  NP_001014358.1

• Accession Number mRNA :

  NM_001014336.1

• Chromosomal Location :

  12q24.31

• Reactivity :

  Anti-Human

• Cross Reactivity :

  Human

• Target Antigen :

  Recombinant human IL-31

• Clone :

  Rabbit IgG

• Applications :

  ELISA, WB

• Purification Method :

  Antigen-affinity purified

• Assay Protocol :

  Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.

• Form :

  Lyophilized

• Buffer :

  PBS

• Reconstitution :

  Water

• Storage Conditions :

  The lyophilized antibody is stable for at least 2 years from date of receipt at -20°C. The reconstituted antibody is stable for at least two weeks at 2-8°C. Frozen aliquots are stable for at least 6 months when stored at -20°C.

• Host or Source :

  Rabbit