IL-31 Recombinant Protein
CAT:
209-M10-073S
Size:
2 µg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
IL-31 Recombinant Protein
- Description: IL-31 is a T-cell derived cytokine that shares several structural and functional characteristics with IL-6, Oncostatin M, LIF, and Cardiotrophin-1. It signals through a receptor complex comprised of GPL (GP130-like, IL-31RA) and OSMR (Oncostatin M receptor). GPL/OSMR signaling is a strong activator of STAT3 and STAT5, and can also activate STAT1, Jak1, and Jak2 signaling pathways. IL-31 regulated immune responses have been implicated in skin physiology and inflammatory skin diseases. Recombinant murine IL-31 is a 15.8 kDa protein containing 140 amino acid residues.
- Synonyms: Il31; 1700013B14Rik
- CAS Number: 9000-83-3
- NCBI Gene ID: 76399
- UniProt: Q6EAL8
- Accession Number: NP_083870.1
- Accession Number mRNA: NM_029594
- Gene Location: 5 F; 5
- Host: E. coli
- Origin Species: Mouse
- Species Reactivity: Mouse
- Sequence: MTCSLSFGAP ISKEDLRTTI DLLKQESQDL YNNYSIKQAS GMSADESIQL PCFSLDREAL TNISVIIAHL EKVKVLSENT VDTSWVIRWL TNISCFNPLN LNISVPGNTD ESYDCKVFVL TVLKQFSNCM AELQAKDNTT C
- Detection Range: Testing in progress.
- Endotoxin: < 0.1 ng/µg of protein (<1EU/µg)
- Purity: > 98% by SDS-PAGE & HPLC analyses
- Length: 140
- Form: Lyophilized
- Molecular Weight: 15.8 kDa
- Shipping Conditions: Room Temperature