IL-28B Recombinant Protein
CAT:
209-M10-039
Size:
20 µg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
IL-28B Recombinant Protein
- Description: IL-28B is a cytokine remotely related to type I interferons and the IL-10 family. Interleukin-28B, interleukin 28A (IL28A), and interleukin 29 (IL29) are 3 closely related cytokine genes which form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by these 3 genes can be induced by viral infection. All 3 cytokines interact with a heterodimeric class II cytokine receptor which consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA).
- Synonyms: Interferon lambda-3, IFN-lambda-3, Interleukin-28B, IL-28B, Ifnl3, Il28, Il28b
- CAS Number: 9000-83-3
- NCBI Gene ID: 338374
- UniProt: Q8CGK6
- Accession Number: NP_796370.1
- Accession Number mRNA: NM_177396.1
- Host: E. coli
- Origin Species: Mouse
- Species Reactivity: Mouse
- Sequence: DPVPRATRLP VEAKDCHIAQ FKSLSPKELQ AFKKAKGAIE KRLLEKDMRC SSHLISRAWD LKQLQVQERP KALQAEVALT LKVWENINDS ALTTILGQPL HTLSHIHSQL QTCTQLQATA EPKPPSRRLS RWLHRLQEAQ SKETPGCLED SVTSNLFQLL LRDLKCVASG DQCV
- Detection Range: The ED50 as determined by an anti-viral assay using human HepG2 cells infected with encephalomyocarditis is less than 30 ng/ml, corresponding to a specific activity of > 3.3 × 104 IU/mg.
- Endotoxin: < 0.1 ng/µg of protein (<1EU/µg)
- Purity: > 97% by SDS-PAGE & HPLC analyses
- Length: 174
- Form: Lyophilized
- Buffer: PBS
- Reconstitution: It is recommended to reconstitute the lyophilized IL-28B in sterile water not less than 100µg/ml, which can then be further diluted to other aqueous solutions.
- Molecular Weight: 19.6 kDa
- Shipping Conditions: Room Temperature
- Storage Conditions: Lyophilized IL-28B although stable at room temperature for 3 weeks, should be stored desiccated below -18°C.