IL-20 Recombinant Protein
CAT:
209-100-230S
Size:
2 µg
Price:
Ask
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
IL-20 Recombinant Protein
- Description: IL-20 is a member of the IL-10 family of regulatory cytokines which includes IL-10, IL-19, IL-20, IL-22, IL-24 and IL-26. Members of this family share partial homology in their amino acid sequences but they are dissimilar in their biological functions. IL-20 is a hematopoietic growth factor capable of stimulating colony formation by CD34+ multipotential progenitors, but not by other progenitor cells. IL-20 signals through a receptor system composed of type I IL-20R-alpha and type II IL-20R-beta. Over-expression of IL-20 in keratinocytes expressing both receptor subunits has been implicated in the induction of inflammatory skin disease. Recombinant human IL-20 is a 35.2 kDa homodimeric protein consisting of two 153 amino acid polypeptide chains.
- Synonyms: IL20; IL-20; IL10D; ZCYTO10
- CAS Number: 9000-83-3
- NCBI Gene ID: 50604
- UniProt: Q9NYY1
- Accession Number: NP_061194.2
- Accession Number mRNA: NM_018724
- Gene Location: 1q32
- Host: E. coli
- Origin Species: Human
- Species Reactivity: Human
- Sequence: MLKTLNLGSC VIATNLQEIR NGFSEIRGSV QAKDGNIDIR ILRRTESLQD TKPANRCCLL RHLLRLYLDR VFKNYQTPDH YTLRKISSLA NSFLTIKKDL RLCHAHMTCH CGEEAMKKYS QILSHFEKLE PQAAVVKALG ELDILLQWME ETE
- Detection Range: Determined by its ability to activate STAT following receptor ligand interaction.
- Endotoxin: < 0.1 ng/µg of protein (<1EU/µg)
- Purity: > 98% by SDS-PAGE & HPLC analyses
- Length: 153
- Form: Lyophilized
- Molecular Weight: 35.2 kDa
- Shipping Conditions: Room Temperature