IL-17F

• Description:

  IL-17F, a member of the IL-17 family of structurally related cytokines, has been shown to stimulate proliferation and activation of T-cells and PBMCs. IL-17F also regulates cartilage matrix turnover and inhibits angiogenesis. Recombinant murine IL-17F is a disulfide-linked homodimer of 30 kDa, consisting of two 134 amino acid residue chains.

• Synonyms:

  IL-17F; ILN; Interleukin; Interleukin-17F; interleukin-24; Interleukin17F; mutant IL-17F

• NCBI Gene ID:

  257630

• UniProt:

  Q7TNI7

• Accession Number:

  NP_665855.2

• Accession Number mRNA:

  NM_145856.2

• Chromosomal Location:

  1 A4; 1

• Reactivity:

  Mouse

• Cross Reactivity:

  Mouse

• Sequence:

  MRKNPKAGVP ALQKAGNCPP LEDNTVRVDI RIFNQNQGIS VPREFQNRSS SPWDYNITRD PHRFPSEIAE AQCRHSGCIN AQGQEDSTMN SVAIQQEILV LRREPQGCSN SFRLEKMLLK VGCTCVKPIV HQAA

• Endotoxin:

  < 0.1 ng/µg of protein (< 1EU/µg)

• Purity:

  > 98% by SDS-PAGE & HPLC analyses

• Bioactivity:

  Data not available.

• Length:

  134

• Form:

  Lyophilized

• Molecular Weight:

  30 kDa

• Host or Source:

  E. coli