IL-17E Recombinant Protein

IL-17E Recombinant Protein

• Description: IL‐17E is a disulfide‐linked homodimer of two 145 amino acid polypeptide chains. It belongs to the IL‐17 family of structurally‐related cytokines that share a highly conserved C‐terminal region, but differ from one another in their N‐terminal regions and in their distinct biological roles. The six known members of this family, IL‐17A through IL‐17F, are secreted as homodimers. IL‐17E stimulates secretion of IL‐8, and induces activation of the transcription factor NF‐κB in cells that express the IL‐17BR receptor. Recombinant Murine IL‐17E is a 35.0 kDa disulfide‐linked homodimer of two 152-amino-acid polypeptide chains.
• Synonyms: Interleukin-17E
• CAS Number: 9000-83-3
• NCBI Gene ID: 140806
• UniProt: Reviewed Data Unavailable
• Gene Location: 14, 14 C3
• Host: E. coli
• Origin Species: Mouse
• Species Reactivity: Mouse
• Sequence: MLRIQEGCSH LPSCCPSKEQ EPPEEWLKWS SASVSPPEPL SHTHHAESCR ASKDGPLNSR AISPWSYELD RDLNRVPQDL YHARCLCPHC VSLQTGSHMD PLGNSVPLYH NQTVFYRRPC HGEEGTHRRY CLERRLYRVS LACVCVRPRV MA
• Detection Range: Measured by its ability to induce GROα (CXCL1) secretion in HT‑29 human colon adenocarcinoma cells.
• Endotoxin: < 0.1 ng/µg of protein (<1EU/µg)
• Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.
• Length: 152
• Form: Lyophilized
• Molecular Weight: 35.0 kDa
• Shipping Conditions: Room Temperature