IL-17E Recombinant Protein
CAT:
209-100-227
Size:
25 µg
Price:
Ask
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
IL-17E Recombinant Protein
- Description: IL-17E is a disulfide-linked homodimer of two 145 amino acid polypeptide chains. It belongs to the IL-17 family of structurally-related cytokines that share a highly conserved C-terminal region, but differ from one another in their N-terminal regions and in their distinct biological roles. The six known members of this family, IL-17A through IL-17F, are secreted as homodimers. IL-17E stimulated secretion of IL-8, and induces activation of the transcription factor NK-kB in cells that express the IL-17BR receptor. Recombinant human IL-17E is a 33.8 kDa disulfide-linked homodimer of two 145 amino acid polypeptide chains.
- Synonyms: IL25; IL17E
- CAS Number: 9000-83-3
- NCBI Gene ID: 64806
- UniProt: Q9H293
- Accession Number: NP_073626.1
- Accession Number mRNA: NM_022789
- Gene Location: 14q11.2
- Host: E. coli
- Origin Species: Human
- Species Reactivity: Human
- Sequence: MYSHWPSCCP SKGQDTSEEL LRWSTVPVPP LEPARPNRHP ESCRASEDGP LNSRAISPWR YELDRDLNRL PQDLYHARCL CPHCVSLQTG SHMDPRGNSE LLYHNQTVFY RRPCHGEKGT HKGYCLERRL YRVSLACVCV RPRVMG
- Detection Range: Determined by its ability to induce IL-8 in human PBMCs using a concentration range of 10-100ng.
- Endotoxin: < 0.1 ng/µg of protein (<1EU/µg)
- Purity: > 98% by SDS-PAGE & HPLC analyses
- Length: 145
- Form: Lyophilized
- Molecular Weight: 33.8 kDa
- Shipping Conditions: Room Temperature