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IL-17D

CAT: 0209-100-226Size: 25 µgDry Ice: NoHazardous: No
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CAT#:0209-100-226Size:25 µg
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Description
IL-17D is a disulfide-linked homodimer of two 185 amino acid polypeptide chains. It belongs to the IL-17 family of structurally-related cytokines that share a highly conserved C-terminal region but differ from one another in their N-terminal regions and in their distinct biological roles. The six known members of this family, IL-17A through IL-17F, are secreted as homodimers. IL-17D has the ability to stimulate the production of IL-6, IL-8, and GM-CSF and inhibits hemopoiesis of myeloid progenitor cells in colony forming assays. Recombinant human IL-17D is a 40.5 kDa disulfide-linked homodimer of two 185 amino acid polypeptide chains.
Synonyms
IL17D; IL27; IL-22; IL-27; IL-17D
NCBI Gene ID
53342
UniProt
Q8TDA2
Accession Number
NP_612141.1
Accession Number mRNA
NM_138284
Chromosomal Location
13q12.11
Reactivity
Human
Cross Reactivity
Mouse
Sequence
APRAGRRPAR PRGCADRPEE LLEQLYGRLA AGVLSAFHHT LQLGPREQAR NASCPAGGRP ADRRFRPPTN LRSVSPWAYR ISYDPARYPR YLPEAYCLCR GCLTGLFGEE DVRFRSAPVY MPTVVLRRTP ACAGGRSVYT EAYVTIPVGC TCVPEPE kDa DSINSSIDKQ GAKLLLGPND APAGP
Endotoxin
< 0.1 ng/µg of protein (< 1EU/µg)
Purity
> 98% by SDS-PAGE & HPLC analyses
Bioactivity
Testing in progress.
Length
185
Form
Lyophilized
Molecular Weight
40.5 kDa
Host or Source
E. coli

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