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IL-7

CAT: 0209-R20-029SSize: 2 µgDry Ice: NoHazardous: No
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CAT#:0209-R20-029SSize:2 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
IL-7 is a hematopoietic growth factor which affects primarily early B and T cells. Produced by thymic stromal cells, spleen cells and keratinocytes, IL-7 can also co-stimulate the proliferation of mature T cells in combination with other factors such as ConA and IL-2. Human and murine IL-7 is cross-species reactive. Recombinant rat IL-7 is a 15.0 kDa protein containing 130 amino acid residues
Synonyms
Il7
NCBI Gene ID
25647
UniProt
Q91Y32
Accession Number
NP_037242.2
Accession Number mRNA
NM_013110
Chromosomal Location
2q23
Reactivity
Rat
Cross Reactivity
Mouse
Sequence
MDCHIKDKDG KAFGSVLMIS INQLDKMTGT DSDCPNNEPN FFKKHLCDDT KEAAFLNRAA RKLRQFLKMN ISEEFNDHLL RVSDGTQTLV NCTSKEEKTI KEQKKNDPCF LKRLLREIKT CWNKILKGSI
Endotoxin
< 0.1 ng/µg of protein (< 1EU/µg)
Purity
> 98% by SDS-PAGE & HPLC analyses
Bioactivity
The ED50 was determined by the dose-dependent stimulation of the proliferation of murine 2E8 cells is < 2.0 ng/ml, corresponding to a specific activity of > 5 x 106 units/mg.
Length
130
Form
Lyophilized
Molecular Weight
15 kDa
Host or Source
E. coli

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