IL-5

• Description :

  Interleukin 5 (IL-5) is a T cell-derived factor that promotes the proliferation, differentiation and activation of eosinophils. In mice, IL-5 is also a growth and differentiation factor for B cells. Various names previously used to describe IL-5 include: Tcell replacing factor (TRF), B cell growth factor II (BCGFII), B cell differentiation factor µ (BCDF µ), eosinophil differentiation factor (EDF) and eosinophil colony-stimulating factor (Eo-CSF) . Biologically active IL-5 is a disulfide-linked homodimer. Rat IL-5 is 94% and 70% identical to mouse and human IL-5, respectively.

• Synonyms :

  Il5; Il-5

• NCBI Gene ID :

  16191

• UniProt :

  P04401

• Accession Number :

  NP_034688.1

• Accession Number mRNA :

  NM_010558.1

• Chromosomal Location :

  11 A5/B1; 11 29.2 cM

• Reactivity :

  Anti-Mouse

• Cross Reactivity :

  Mouse

• Target Antigen :

  Recombinant Mouse IL-5

• Clone :

  (#17L32)

• Applications :

  FC, N/B

• Purification Method :

  Protein G/A chromatography

• Assay Protocol :

  Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

• Form :

  Lyophilized

• Buffer :

  PBS

• Reconstitution :

  PBS

• Storage Conditions :

  Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.

• Host or Source :

  Rat

• Isotype :

  IgG2