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IL-3

CAT: 0209-103-M420Size: 50 µgDry Ice: NoHazardous: No
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CAT#:0209-103-M420Size:50 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
IL-3 is a hematopoietic growth factor that promotes the survival, differentiation and proliferation of committed progenitor cells of the megakaryocyte, granulocyte-macrophage, erythroid, eosinophil, basophil and mast cell lineages. Produced by T cells, mast cells and eosinophils, IL-3 enhances thrombopoieses, phagocytosis, and antibody-mediated cellular cytotoxicity. Its ability to activate monocytes suggests that IL-3 may have additional immunoregulatory roles. Many of the IL-3 activities depend upon co-stimulation with other cytokines. IL-3 is species-specific, variably glycosylated cytokine. Recombinant murine IL-3 is a 15.1 kDa globular protein containing 135 amino acid residues.
Synonyms
Il3; BPA; PSF; HCGF; Il-3; MCGF; Csfmu
NCBI Gene ID
16187
UniProt
P01586
Accession Number
NP_034686.2
Accession Number mRNA
NM_010556.4
Chromosomal Location
11 B1; 11 28.5 cM
Reactivity
Anti-Mouse
Cross Reactivity
Mouse
Target Antigen
Recombinant mouse protein of IL-3
Clone
(#9D19)
Applications
WB, N
Purification Method
Protein G/A chromatography
Assay Protocol
Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Host or Source
Rat
Isotype
IgG2

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