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IL-3

CAT: 0209-101-M712Size: 50 µgDry Ice: NoHazardous: No
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CAT#:0209-101-M712Size:50 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
IL-3 is a hematopoietic growth factor that promotes the survival, differentiation and proliferation of committed progenitor cells of the megakaryocyte, granulocyte-macrophage, erythroid, eosinophil, basophil and mast cell lineages. Produced by T cells, mast cells and eosinophils, IL-3 enhances thrombopoieses, phagocytosis, and antibody-mediated cellular cytotoxicity. Its ability to activate monocytes suggests that IL-3 may have additional immunoregulatory roles. Many of the IL-3 activities depend upon co-stimulation with other cytokines. IL-3 is species-specific, variably glycosylated cytokine. Recombinant human IL-3 is a 15.0 kDa globular protein containing 133 amino acid residues.
Synonyms
IL3; IL-3; MCGF; MULTI-CSF
NCBI Gene ID
3562
UniProt
P08700
Accession Number
NP_000579
Accession Number mRNA
NM_000588
Chromosomal Location
5q31.1
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Recombinant human IL-3
Clone
(#10B35)
Applications
WB, IHC (F), N
Purification Method
Protein G chromatography
Assay Protocol
Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Host or Source
Mouse
Isotype
IgG1

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