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IL-1F8

CAT: 0209-101-M499Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0209-101-M499Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
The IL-1 family of cytokines is a set of structurally related molecules that are primary mediators of inflammation. This family now consists of 11 cytokines and 9 cell-surface receptors, the best characterized of which are IL-1α, IL-1β, IL-1 receptor antagonist (IL-1ra), and IL-18. Seven novel members were recently identified from DNA databases almost simultaneously by several different groups, and to reduce confusion, a systematic nomenclature was proposed. IL-1F6, IL-1F8, and IL-1F9 have all reported proinflammatory properties. IL-1F5 shares 52% amino acid similarity with IL-1ra and as such antagonizes IL-1F6 and IL-1F9 at the IL-1R3 (RAcP) –IL-1R6 (Rrp2) receptor complex. IL-1F7 acts as an attenuator of IL-18 activity and may act as an inhibitor of innate immune signaling.
Synonyms
IL36B; FIL1; FIL1H; IL1F8; IL1H2; IL-1F8; IL-1H2; IL1-ETA; FIL1- (ETA) ; FILI- (ETA)
NCBI Gene ID
27177
UniProt
Q9NZH7
Accession Number
NP_055253.2
Accession Number mRNA
NM_014438.4
Chromosomal Location
2q14
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Recombinant human IL-1F8
Clone
(#2Q27)
Applications
WB
Purification Method
Protein G chromatography
Assay Protocol
Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Host or Source
Mouse
Isotype
IgG1

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MBS2535328-01IL-1F8 Polyclonal Antibody
sc-146211-PRIL-1F8 (m) -PR
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