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IGF-1 Receptor

CAT: 0209-101-M455Size: 50 µgDry Ice: NoHazardous: No
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CAT#:0209-101-M455Size:50 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
IGF-I receptor is a disulfide-linked heterotetrameric transmembrane protein consisting of two alpha and two beta subunits. Both the alpha and beta subunits are encoded within a single receptor precursor cDNA. The proreceptor polypeptide is proteolytically cleaved and disulfide-linked to yield the mature heterotetrameric receptor. The alpha subunit of IGF-I receptor is extracellular while the beta subunit has an extracellular domain, a transmembrane domain and a cytoplasmic tyrosine kinase domain. The IGF-I receptor is highly expressed in all cell types and tissues.
Synonyms
Igf1r; hyft; CD221; IGF-1R; D930020L01; A330103N21Rik
NCBI Gene ID
16001
UniProt
P08069
Accession Number
NP_000866.1
Accession Number mRNA
NM_000875.3
Chromosomal Location
7 D1; 7 33.0 cM
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Recombinatn human IGF-I R EC domain
Clone
(#5J32)
Applications
WB, N
Purification Method
Protein G chromatography
Assay Protocol
Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Host or Source
Mouse
Isotype
IgG1

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