IFN omega Recombinant Protein

IFN omega Recombinant Protein

• Description: IFN-ω is a type I interferon, which can be induced by virus-infected leukocytes. Members of the type I interferon family, which includes IFN-alpha, IFN-ß, and IFN-ω, signal through IFNAR-1/IFNAR-2 receptor complex, and exert antiviral and antiproliferative activities. IFN-ω exhibits about 75% sequence homology with IFN-alpha, and contains two conserved disulfide bonds, which are necessary for full biological activity. Recombinant Human IFN-ω is a 19.9 kDa protein consisting of 172 amino acid residues.
• Synonyms: IFNW1; Interferon omega
• CAS Number: 9000-83-3
• NCBI Gene ID: 3467
• UniProt: P05000
• Accession Number: NP_002168.1
• Accession Number mRNA: NM_002177
• Gene Location: 9p22
• Host: E. coli
• Origin Species: Human
• Species Reactivity: Human
• Sequence: CDLPQNHGLL SRNTLVLLHQ MRRISPFLCL KDRRDFRFPQ EMVKGSQLQK AHVMSVLHEM LQQIFSLFHT ERSSAAWNMT LLDQLHTGLH QQLQHLETCL LQVVGEGESA GAISSPALTL RRYFQGIRVY LKEKKYSDCA WEVVRMEIMK SLFLSTNMQE RLRSKDRDLG SS
• Detection Range: The ED50 was determined by a cytotoxicity assay using Human TF-1 cells is ≤ 0.01 ng/ml, corresponding to a specific activity of ≥ 1 x 108 units/mg.
• Endotoxin: < 0.1 ng/µg of protein (<1EU/µg)
• Purity: > 98% by SDS-PAGE & HPLC analyses
• Length: 172
• Form: Lyophilized
• Molecular Weight: 19.9 kDa
• Shipping Conditions: Room Temperature