Recombinant Human IFN- Omega protein

Recombinant Human IFN- Omega protein

• Background: Interferon-Omega (IFN-ω) coded by IFNW1 gene in human, is a number of the type I interferon family, which includes IFN-α, IFN-β, and IFN-ω. The IFNAR-1/IFNAR-2 receptor complex can help with the signal transduction, followed the antiviral or the antiproliferative actions. IFN-ω is derived from IFN-α/β and share 75 % sequence with IFN-α. It has two intramolecular disulfide bonds which are crucial for activities. Mire-Sluis et al have described bioassays for IFN-α, IFN-β, and IFN-ω that exploit the ability of these factors to inhibit proliferation of TF-1 cells induced by GM-CSF. The bioassays can be used also with Epo and TF-1 cells, or Epo and Epo-transfected UT-7 cells.
• CAS Number: 9000-83-3
• Reconstitution: Lyophilized from a .2 μm filtered solution of PBS, pH 7.4.
• Molecular Weight: Approximately 2. kDa, containing 172 amino acid residues with two conserved disulfide bonds.