GLP-1 Recombinant Protein
CAT:
209-100-339S
Size:
200 µg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
GLP-1 Recombinant Protein
- Description: GLP-1 is a proglucagon-derived peptide hormone secreted primarily by intestinal L cells during feeding. Its major physiological function is stimulation of pancreatic β-cells to release appropriate amounts of insulin after glucose absorption. Other biological actions exhibited by GLP-1 include suppression of plasma glucagons levels, inhibition of gastric motility, and promotion of satiety. The secretion of GLP-1 from intestinal L cells is stimulated by nutrients, hormones, and neural inputs. On the other hand, insulin has been reported to inhibit GLP-1 release, indicating that a feedback loop mechanism regulates GLP-1 secretion. In addition to being the precursor of GLP-1, proglucagon, whose primary structure is highly conserved in mammalian species, is also the precursor for other members of the glucagon family of peptide hormones including glicentin-related pancreatic peptide (GRPP), glucagons, and GLP-2. Recombinant human GLP-1 is a 3.3 kDa consisting of 31 amino acid residues.
- Synonyms: GLP1; GLP2; GRPP
- CAS Number: 9000-83-3
- NCBI Gene ID: 2641
- UniProt: P01275
- Accession Number: NP_002045.1
- Accession Number mRNA: NM_002054.4
- Gene Location: 2q36-q37
- Host: E. coli
- Origin Species: Human
- Species Reactivity: Human
- Sequence: HAEGTFTSDV SSYLEGQAAK EFIAWLVKGR G
- Detection Range: Data not available.
- Endotoxin: < 0.1 ng/µg of protein (<1EU/µg)
- Purity: > 98% by SDS-PAGE & HPLC analyses
- Length: 31
- Form: Lyophilized
- Molecular Weight: 3.3 kDa
- Shipping Conditions: Room Temperature