Flt-3 Ligand Recombinant Protein
CAT:
209-100-026-SC
Size:
50 µg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Flt-3 Ligand Recombinant Protein
- Description: Flt3-ligand (flk2-ligand) stimulates the proliferation and colony formation of certain BM precursor cells including CD34+ cells. Flt3-ligand produced in E. coli is a soluble non-glycosylated 17.6 kDa polypeptide containing 155 amino acid residues which comprises the extracellular domain of the transmembrane flt3-ligand protein.
- Synonyms: FLT3; FLK2; STK1; CD135; FLK-2
- CAS Number: 9000-83-3
- NCBI Gene ID: 2323
- UniProt: P49771
- Accession Number: NP_001450.2
- Accession Number mRNA: NM_001459.3
- Gene Location: 19q13.3
- Host: E. coli
- Origin Species: Human
- Species Reactivity: Human
- Sequence: TQDCSFQHSP ISSDFAVKIR ELSDYLLQDY PVTVASNLQD EELCGGLWRL VLAQRWMERL KTVAGSKMQG LLERVNTEIH FVTKCAFQPP PSCLRFVQTN ISRLLQETSE QLVALKPWIT RQNFSRCLEL QCQPDSSTLP PPWSPRPLEA TAPTA
- Detection Range: Determined by the dose-dependent stimulation of the proliferation of human AML5 cells. The expected ED50 for this effect is 0,5 – 2ng/ml.
- Endotoxin: < 0.1 ng/µg of protein (<1EU/µg)
- Purity: > 98% by SDS-PAGE & Coomassie stain
- Length: 155
- Form: Lyophilized
- Molecular Weight: 17.6 kDa
- Shipping Conditions: Room Temperature