Flt-3 Ligand Recombinant Protein

• Description:

  Flt3-ligand (flk2-ligand) stimulates the proliferation and colony formation of certain BM precursor cells including CD34+ cells. Flt3-ligand produced in E. coli is a soluble non-glycosylated 17.6 kDa polypeptide containing 155 amino acid residues which comprises the extracellular domain of the transmembrane flt3-ligand protein.

• Synonyms:

  FLT3; FLK2; STK1; CD135; FLK-2

• CAS Number:

  9000-83-3

• NCBI Gene ID:

  2323

• UniProt:

  P49771

• Accession Number:

  NP_001450.2

• Accession Number mRNA:

  NM_001459.3

• Gene Location:

  19q13.3

• Host:

  E. coli

• Origin Species:

  Human

• Species Reactivity:

  Human

• Sequence:

  TQDCSFQHSP ISSDFAVKIR ELSDYLLQDY PVTVASNLQD EELCGGLWRL VLAQRWMERL KTVAGSKMQG LLERVNTEIH FVTKCAFQPP PSCLRFVQTN ISRLLQETSE QLVALKPWIT RQNFSRCLEL QCQPDSSTLP PPWSPRPLEA TAPTA

• Detection Range:

  Determined by the dose-dependent stimulation of the proliferation of human AML5 cells. The expected ED50 for this effect is 0,5 – 2ng/ml.

• Endotoxin:

  < 0.1 ng/µg of protein (<1EU/µg)

• Purity:

  > 98% by SDS-PAGE & Coomassie stain

• Length:

  155

• Form:

  Lyophilized

• Molecular Weight:

  17.6 kDa

• Shipping Conditions:

  Room Temperature