FGF-23

CAT: 209-102-P109Size: 100 µgDry Ice: NoHazardous: No
100 µgSelected
AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
The FGF family plays a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-23, FGF-21 and FGF-19 constitute an atypical FGF subfamily whose ligands act as circulating hormones and require the participation of a Klotho protein as a co-receptor for their signaling. FGF-23 is a bone-derived hormone that acts in the kidney to regulate phosphate homeostasis and vitamin D metabolism. The signaling receptor for FGF-23, a Klotho-FGFR1 (IIIc) complex, is an essential regulator of the renal sodium phosphate co-transporter and key vitamin D-metabolizing enzymes CYP27B1 and CYP24A1.
Synonyms
FGF23; ADHR; HYPF; HPDR2; PHPTC ; fgf 23
NCBI Gene ID
8074
UniProt
Q9GZV9
Accession Number
NP_065689.1
Accession Number mRNA
NM_020638
Chromosomal Location
12p13.3
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Recombinant human FGF-23
Clone
Rabbit IgG
Applications
ELISA, WB
Purification Method
Antigen-affinity purified
Form
Lyophilized
Buffer
PBS
Reconstitution
Water
Host or Source
Rabbit