FGF-21 Recombinant Protein

FGF-21 Recombinant Protein

• Description: FGF-21 is a secreted growth factor that is a member of the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-21, in the presence of β-Klotho as a protein cofactor, signals through the FGFR 1c and 4 receptors, and stimulates insulin-independent glucose uptake by adipocytes. Recombinant Murine FGF-21 is a 20.1 kDa protein containing 182 amino acid residues.
• Synonyms: Fibroblast Growth Factor-21, FGFL
• CAS Number: 9000-83-3
• NCBI Gene ID: 56636
• UniProt: Q9JJN1
• Accession Number: NP_064397.1
• Accession Number mRNA: NM_020013.4
• Host: E. coli
• Origin Species: Mouse
• Species Reactivity: Mouse
• Sequence: MAYPIPDSSP LLQFGGQVRQ RYLYTDDDQD TEAHLEIRED GTVVGAAHRS PESLLELKAL KPGVIQILGV KASRFLCQQP DGALYGSPHF DPEACSFREL LLEDGYNVYQ SEAHGLPLRL PQKDSPNQDA TSWGPVRFLP MPGLLHEPQD QAGFLPPEPP DVGSSDPLSM VEPLQGRSPS YAS
• Detection Range: Determined by its ability to stimulate the proliferation of murine NIH-3T3 cells.
• Endotoxin: < 0.1 ng/µg of protein (<1EU/µg)
• Purity: ≥ 95% by SDS-PAGE gel and HPLC analyses
• Length: 182
• Form: Lyophilized
• Molecular Weight: 20.1 kDa
• Shipping Conditions: Room Temperature