FGF-21 Recombinant Protein
CAT:
209-100-337S
Size:
5 µg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No

FGF-21 Recombinant Protein
- Description: FGF-21 is a secreted growth factor that is a member of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-21, in the presence of betaKlotho as a protein cofactor, signals through the FGFR 1c and 4 receptors and stimulates insulin independent glucose uptake by adipocytes. Recombinant human FGF-21 is a 19.5 kDa protein containing 182 amino acid residues.
- Synonyms: FGF21
- CAS Number: 9000-83-3
- NCBI Gene ID: 26291
- UniProt: Q9NSA1
- Accession Number: NP_061986.1
- Accession Number mRNA: NM_019113
- Gene Location: 19q13.1-qter
- Host: E. coli
- Origin Species: Human
- Species Reactivity: Human
- Sequence: MHPIPDSSPL LQFGGQVRQR YLYTDDAQQT EAHLEIREDG TVGGAADQSP ESLLQLKALK PGVIQILGVK TSRFLCQRPD GALYGSLHFD PEACSFRELL LEDGYNVYQS EAHGLPLHLP GNKSPHRDPA PRGPARFLPL PGLPPALPEP PGILAPQPPD VGSSDPLSMV GPSQGRSPSY AS
- Detection Range: FGF-21, in the absence of betaKlotho, shows weak activity of thymidine uptake by BaF3 cells expressing FGF receptors.
- Endotoxin: < 0.1 ng/µg of protein (<1EU/µg)
- Purity: > 90% by SDS-PAGE & HPLC analyses
- Length: 182
- Form: Lyophilized
- Molecular Weight: 19.5 kDa
- Shipping Conditions: Room Temperature