FGF-20

CAT: 0209-100-170SSize: 3 µgDry Ice: NoHazardous: No
CAT#:0209-100-170SSize:3 µg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
FGF-20 is secreted heparin binding growth factor that is a member of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-20 signals through the FGFR 2c and 3c and is expressed during limb and brain development. Recombinant human FGF-20 is a 23.2 kDa protein containing 209 amino acid residues.
Synonyms
FGF20; FGF-20
NCBI Gene ID
26281
UniProt
Q9NP95
Accession Number
NP_062825.1
Accession Number mRNA
NM_019851
Chromosomal Location
8p22
Reactivity
Human
Cross Reactivity
Monkey, Mouse
Sequence
PLAEVGGFLG GLEGLGQQVG SHFLLPPAGE RPPLLGERRS AAERSARGGP GAAQLAHLHG ILRRRQLYCR TGFHLQILPD GSVQGTRQDH SLFGILEFIS VAVGLVSIRG VDSGLYLGMN DKGELYGSEK LTSECIFREQ FEENWYNTYS SNIYKHGDTG RRYFVALNKD GTPRDGARSK RHQKFTHFLP RPVDPERVPE LYKDLLMYT
Assay Protocol
Reconstitute in 10mM Tris, pH 7.6, to a concentration of 0.1-1.0 mg/ml
Endotoxin
< 0.1 ng/µg of protein (< 1EU/µg)
Purity
> 90% by SDS-PAGE & HPLC analyses
Bioactivity
The ED50 as determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF-receptors is ≤ 10 ng/ml, corresponding to a specific activity of ≥ 1 x 105 units/mg.
Length
209
Form
Lyophilized
Buffer
25mM Tris, pH 7.6 + 1.5M NaCl
Reconstitution
25mM Tris, pH 7.6
Molecular Weight
23.2 kDa
Host or Source
E. coli

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