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FGF-19 (Animal Free)

CAT: 0209-100-169-AFSize: 25 µgDry Ice: NoHazardous: No
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CAT#:0209-100-169-AFSize:25 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
The FGF family plays central roles during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-19, a member of the FGF family, is a high-affinity heparin dependent ligand for FGFR4. FGF-19 is expressed during brain development and embryogenesis. Recombinant Human FGF-19 is a 21.8 kDa protein containing 195 amino acid residues.
Synonyms
FGF19
NCBI Gene ID
9965
UniProt
O95750
Accession Number
NP_005108.1
Accession Number mRNA
NM_005117
Chromosomal Location
11q13.1
Reactivity
Human
Cross Reactivity
Mouse, Hamster
Sequence
MRPLAFSDAG PHVHYGWGDP IRLRHLYTSG PHGLSSCFLR IRADGVVDCA RGQSAHSLLE IKAVALRTVA IKGVHSVRYL CMGADGKMQG LLQYSEEDCA FEEEIRPDGY NVYRSEKHRL PVSLSSAKQR QLYKNRGFLP LSHFLPMLPM VPEEPEDLRG HLESDMFSSP LETDSMDPFG LVTGLEAVRS PSFEK
Endotoxin
< 0.01 ng/µg of protein (< 0.1 EU/µg)
Purity
≥ 95% by SDS-PAGE gel and HPLC analyses.
Bioactivity
Determined by a cell proliferation assay using Balb/c 3T3 cells. The expected ED50 for this effect is 100-150 ng/ml.
Length
195
Form
Lyophilized
Molecular Weight
21.8 kDa
Host or Source
E. coli

UniProtKB · O95750

Fibroblast growth factor 19

FGF19_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O95750
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
FGF19
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
FGF-19
EC number
—
Processing
Precursor
Secondary accessions
—
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

Disulfide bond

Molecular function

Growth factor

Cellular component

Secreted

Domain

Signal

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