FGF-16

• Description:

  FGF-16 is a heparin binding growth factor that is a member of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-16 signals through FGFR 2c and 3c. FGF-16 plays a role in the development of the central nervous system. Recombinant human FGF-16 is a 23.7 kDa protein consisting of 207 amino acid residues.

• Synonyms:

  FGF16; FGF-16

• NCBI Gene ID:

  8823

• UniProt:

  O43320

• Accession Number:

  NP_003859

• Accession Number mRNA:

  NM_003868

• Chromosomal Location:

  Xq13

• Reactivity:

  Human

• Cross Reactivity:

  Mouse

• Sequence:

  AEVGGVFAS LDWDLHGFSS SLGNVPLADS PGFLNERLGQ IEGKLQRGSP TDFAHLKGIL RRRQLYCRTG FHLEIFPNGT VHGTRHDHSR FGILEFISLA VGLISIRGVD SGLYLGMNER GELYGSKKLT RECVFREQFE ENWYNTYAST LYKHSDSERQ YYVALNKDGS PREGYRTKRH QKFTHFLPRP VDPSKLPSMS RDLFHYR

• Endotoxin:

  < 0.1 ng/µg of protein (< 1EU/µg)

• Purity:

  > 95% by SDS-PAGE & HPLC analyses

• Bioactivity:

  The biological activity was determined by the FGF-10-induced proliferation of 4MBr-5 cells.

• Length:

  207

• Form:

  Lyophilized

• Molecular Weight:

  23.7 kDa

• Host or Source:

  E. coli