FGF-6 Recombinant Protein

FGF-6 Recombinant Protein

• Description: FGF-6 is a secreted heparin binding growth factor that is a member of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-6 is expressed in leukemia cell lines with platelet megakaryocytic differentiation potential. It signals through FGFR 1c, 2c, and 4. Recombinant human FGF-6 is an 18.7 kDa protein consisting of 168 amino acid residues.
• Synonyms: FGF6; HST2; HBGF-6
• CAS Number: 9000-83-3
• NCBI Gene ID: 2251
• UniProt: P10767
• Accession Number: NP_066276
• Accession Number mRNA: NM_020996
• Gene Location: 12p13
• Host: E. coli
• Origin Species: Human
• Species Reactivity: Human
• Sequence: GTRANNTLL DSRGWGTLLS RSRAGLAGEI AGVNWESGYL VGIKRQRRLY CNVGIGFHLQ VLPDGRISGT HEENPYSLLE ISTVERGVVS LFGVRSALFV AMNSKGRLYA TPSFQEECKF RETLLPNNYN AYESDLYQGT YIALSKYGRV KRGSKVSPIM TVTHFLPRI
• Detection Range: The ED50 as determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF-receptors is ≤ 0.5 ng/ml, corresponding to a specific activity of ≥ 2 x 106 units/mg.
• Endotoxin: < 0.1 ng/µg of protein (<1EU/µg)
• Purity: > 95% by SDS-PAGE & HPLC analyses
• Length: 168
• Form: Lyophilized
• Buffer: 10 mM NaP, pH 7.2 + 50 mM NaCl
• Molecular Weight: 18.7 kDa
• Shipping Conditions: Room Temperature