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Fetuin-A

CAT: 0209-103-M381Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0209-103-M381Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Mouse Fetuin A, also known as α2-Heremans-Schmid glycoprotein, is encoded by the AHSG gene. It has been also called "countertrypsin" because of its ability to inhibit trypsin. It is a major plasma protein and a member of the cystatin superfamily of protease inhibitors. It is expressed by hepatocytes, the principal cell source, and by monocyte/macrophages. The major form of plasma Fetuin A corresponds to two disulfide bondlinked chains derived from the single chain. FetuinA has a number of functions. It is a negative acutephase protein with normal circulating levels in adults (300-600 μg/mL), which fall significantly (30-50%) during injury and infection. It enhances entry of cationic inhibitors into macrophages. It inhibits both insulin receptor autophosphorylation and undesirable calcification.
Synonyms
Ahsg; fetuin-A
NCBI Gene ID
11625
UniProt
P29699
Accession Number
NP_038493.1
Accession Number mRNA
NM_013465.2
Chromosomal Location
16 B1; 16 15.0 cM
Reactivity
Anti-Mouse
Cross Reactivity
Mouse
Target Antigen
Recombinant mouse Fetuin-A
Clone
(#4N42)
Applications
WB
Purification Method
Protein G/A chromatography
Assay Protocol
Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Host or Source
Rat
Isotype
IgG2

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