Eotaxin-3

CAT: 0209-101-M19Size: 500 µgDry Ice: NoHazardous: No
CAT#:0209-101-M19Size:500 µg
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Description
Eotaxin3, also named CCL26 or SCYA26, is a novel human CC chemokine that maps to chromosome 7q11.2, within 40 kilobases of the Eotaxin2 loci. Eotaxin3/ CCL26 has been shown to be constitutively expressed in the heart and ovary. In addition, low levels of Eotaxin3/ CCL26 expression can also be detected in various tissues. The expression of Eotaxin 3/CCL26 in vascular endothelial cells has been shown to be upregulated by IL13 and IL4. Eotaxin3/ CCL26 cDNA encodes a 94 amino acid (aa) residue protein with a putative signal peptide of either 23 or 26 aa residues. Eotaxin3/ CCL26 induces calcium flux in eosinophils as well as in CCR3transfected cells. Eotaxin 3/ CCL26 has also been shown to cross-desensitize cells to other CCR3 ligands.
Synonyms
CCL26; IMAC; TSC-1; MIP-4a; SCYA26; MIP-4alpha
NCBI Gene ID
10344
UniProt
Q9Y258
Accession Number
NP_006063
Accession Number mRNA
NM_006072
Chromosomal Location
7q11.23
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Recombinant Human Eotaxin-3 (CCL26)
Applications
ELISA, WB, N
Purification Method
Protein A chromatography
Assay Protocol
Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.
Form
Lyophilized from PBS
Buffer
PBS
Reconstitution
Water
Storage Conditions
The lyophilized antibody is stable for at least 2 years from date of receipt at -20°C. The reconstituted antibody is stable for at least two weeks at 2-8°C. Frozen aliquots are stable for at least 6 months when stored at -20°C.
Host or Source
Mouse
Isotype
IgG1, kappa

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