Complement MASP3

CAT: 0209-101-M336Size: 50 µgDry Ice: NoHazardous: No
CAT#:0209-101-M336Size:50 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Nine serine proteases and their cofactors participate in the three pathways that lead to complement activation. C1r and C1s are the first two proteases that trigger the classical pathway. Three mannan-binding lectin-associated serine proteases (MASPs) are involved in the MBL pathway. C2 is involved in both the classical and the MBL pathways. Factor D is the first protease that activates the alternative pathway, which also includes proteases factor B and factor I. C3 plays a central role in both classical and alternative pathways. C3d, one of its fragments, binds to CR2. C5 is common to all three pathways, and C5a belongs to a family of related proteins known as anaphylatoxins.
Synonyms
MASP1; MAP1; MASP; RaRF; CRARF; MASP3; MAp44; PRSS5; CRARF1
NCBI Gene ID
5648
UniProt
P48740
Accession Number
NP_001027019.1
Accession Number mRNA
NM_001031849.2
Chromosomal Location
3q27-q28
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Human recombinant Complement MASP3
Clone
(#4F19)
Applications
WB
Purification Method
Protein G chromatography
Assay Protocol
Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Host or Source
Mouse
Isotype
IgG2

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