Complement Factor D (Adipsin)

CAT: 209-101-M278Size: 100 µgDry Ice: NoHazardous: No
100 µgSelected
AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Complement Factor D, also known as adipsin, is a serine protease that catalyzes the initial proteolytic step in the alternative pathway of complement. It is an exceptionally specific protease and the only known protein substrate is factor B in complex with C3.3 Factor D protease activity is regulated by reversible conformational changes, which differs from the majority of serine proteases whose regulation involves either activation by processing of the zymogens or inactivation by binding of the inhibitors.
Synonyms
CFD; DF; ADN; PFD; ADIPSIN
NCBI Gene ID
1675
UniProt
P00746
Accession Number
NP_001919.2
Accession Number mRNA
NM_001928.2
Chromosomal Location
19p13.3
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Human recombinant Complement Factor D (Adipsin)
Clone
(#4S49)
Applications
Capture Ab
Purification Method
Protein G chromatography
Assay Protocol
Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.
Host or Source
Mouse
Isotype
IgG2