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CD23

CAT: 0209-101-M196Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0209-101-M196Size:100 µg
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Description
CD23, also known as Fc epsilon RII, is a type 2 transmembrane C-type lectin that binds IgE, CD21, CD11b and CD11c. It is expressed on a variety of hematopoietic cells and functions in allergic immune responses.
Synonyms
FCER2; CD23; FCE2; CD23A; IGEBF; CLEC4J
NCBI Gene ID
2208
UniProt
P06734
Accession Number
NP_001993.2
Accession Number mRNA
NM_002002.4
Chromosomal Location
19p13.3
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Human recombinant CD23 (Fc epsilon RII) EC domain
Clone
(#2C54)
Applications
Capture Ab
Purification Method
Protein G chromatography
Assay Protocol
Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.
Host or Source
Mouse
Isotype
IgG2

UniProtKB · P06734

Low affinity immunoglobulin epsilon Fc receptor

FCER2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P06734
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
FCER2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
—
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Ligand

CalciumLectinMetal-binding

Cellular component

Cell membraneMembraneSecreted

PTM

Disulfide bondGlycoproteinLipoproteinPalmitateProteoglycan

Molecular function

IgE-binding proteinReceptor

Domain

RepeatSignal-anchorTransmembraneTransmembrane helix