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CD19

CAT: 0209-101-M194Size: 50 µgDry Ice: NoHazardous: No
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CAT#:0209-101-M194Size:50 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
B-lymphocyte antigen CD19 is a surface protein of the immunoglobulin superfamily. It binds to the B cell receptor on the cell surface of B cells and lowers the threshold of its activability. Thus, overexpression of CD19 in mice, as well as knockout mice, shows that CD19 affects the signaling threshold of receptors that regulate B lymphocyte selection, activation, and differentiation. At the molecular level, CD19 is involved in the activation of phosphatidylinositol 4,5-bisphosphate 3-kinases (PI3K) . It is glycosylated and phosphorylated. Translated with www.DeepL.com/Translator (free version)
Synonyms
B-lymphocyte surface antigen B4, Differentiation antigen CD19, T-cell surface antigen Leu-12
NCBI Gene ID
930
UniProt
P15391
Accession Number
NP_001171569.1
Accession Number mRNA
NM_001178098.1
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Recombinant human CD19
Clone
(#13Q82)
Applications
FC
Purification Method
Protein G chromatography
Assay Protocol
Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.
Host or Source
Mouse
Isotype
IgG1

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