CD19

• Description :

  B-lymphocyte antigen CD19 is a surface protein of the immunoglobulin superfamily. It binds to the B cell receptor on the cell surface of B cells and lowers the threshold of its activability. Thus, overexpression of CD19 in mice, as well as knockout mice, shows that CD19 affects the signaling threshold of receptors that regulate B lymphocyte selection, activation, and differentiation. At the molecular level, CD19 is involved in the activation of phosphatidylinositol 4,5-bisphosphate 3-kinases (PI3K) . It is glycosylated and phosphorylated. Translated with www.DeepL.com/Translator (free version)

• Synonyms :

  B-lymphocyte surface antigen B4, Differentiation antigen CD19, T-cell surface antigen Leu-12

• NCBI Gene ID :

  930

• UniProt :

  P15391

• Accession Number :

  NP_001171569.1

• Accession Number mRNA :

  NM_001178098.1

• Reactivity :

  Anti-Human

• Cross Reactivity :

  Human

• Target Antigen :

  Recombinant human CD19

• Clone :

  (#13Q82)

• Applications :

  FC

• Purification Method :

  Protein G chromatography

• Assay Protocol :

  Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

• Form :

  Lyophilized

• Buffer :

  PBS

• Reconstitution :

  PBS

• Storage Conditions :

  Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.

• Host or Source :

  Mouse

• Isotype :

  IgG1