CD19

• Description:

  B-lymphocyte antigen CD19 is a surface protein of the immunoglobulin superfamily. It binds to the B cell receptor on the cell surface of B cells and lowers the threshold of its activability. Thus, overexpression of CD19 in mice, as well as knockout mice, shows that CD19 affects the signaling threshold of receptors that regulate B lymphocyte selection, activation, and differentiation. At the molecular level, CD19 is involved in the activation of phosphatidylinositol 4,5-bisphosphate 3-kinases (PI3K) . It is glycosylated and phosphorylated. Translated with www.DeepL.com/Translator (free version)

• Synonyms:

  B-lymphocyte surface antigen B4, Differentiation antigen CD19, T-cell surface antigen Leu-12

• NCBI Gene ID:

  930

• UniProt:

  P15391

• Accession Number:

  NP_001171569.1

• Accession Number mRNA:

  NM_001178098.1

• Reactivity:

  Anti-Human

• Cross Reactivity:

  Human

• Target Antigen:

  Recombinant human CD19

• Clone:

  (#13Q82)

• Applications:

  FC

• Purification Method:

  Protein G chromatography

• Assay Protocol:

  Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

• Form:

  Lyophilized

• Buffer:

  PBS

• Reconstitution:

  PBS

• Storage Conditions:

  Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.

• Host or Source:

  Mouse

• Isotype:

  IgG1