BMP-13 / CDMP-2 (Animal Free) Recombinant Protein
CAT:
209-100-137S-AF
Size:
10 µg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
BMP-13 / CDMP-2 (Animal Free) Recombinant Protein
- Description: BMP-13 is expressed in hypertrophic chondrocytes during embryonic development of long bones. Continued postnatal expression of BMP-13 in articular cartilage suggests that it plays a regulatory role in the growth and maintenance of articular cartilage. Adenovirus-mediated BMP-13 gene transfer to rabbit bone marrow stem cells have been reported to augment periosteal repair of osteochondral defects. The functional form of BMP-13/CDMP-2 is a disulfide-linked homodimer of two 120 amino-acid polypeptide chains. This 27.5 kDa protein is obtained by proteolytic processing of a biologically inactive precursor protein of 97.7kDa. Recombinant Human BMP-13/CDMP-2 is a 27.0 kDa homodimeric disulfide-linked protein consisting of two 120 amino acid polypeptide chains.
- Synonyms: GDF6; KFM; KFS; KFS1; KFSL; SGM1; BMP13; CDMP2; MCOP4; SCDO4; MCOPCB6
- CAS Number: 9000-83-3
- NCBI Gene ID: 392255
- UniProt: P43028
- Accession Number: NP_038554.1
- Accession Number mRNA: NM_013526.1
- Gene Location: 8q22.1
- Host: E. coli
- Origin Species: Human
- Species Reactivity: Mouse, Human
- Sequence: TAFASRHGKR HGKKSRLRCS KKPLHVNFKE LGWDDWIIAP LEYEAYHCEG VCDFPLRSHL EPTNHAIIQT LMNSMDPGST PPSCCVPTKL TPISILYIDA GNNVVYKQYE DMVVESCGCR
- Detection Range: Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells. The expected ED50 for this effect is 2.0-3.0 µg/ml.
- Endotoxin: Endotoxin level is < 0.01 ng/ug of protein (< 0.1 EU/ug)
- Purity: ≥ 95% by SDS-PAGE gel and HPLC analyses.
- Length: 120
- Form: Lyophilized
- Molecular Weight: 27.0 kDa
- Shipping Conditions: Room Temperature