RegisterLogin

BMP-7

CAT: 0209-102-P105Size: 100 µgDry Ice: NoHazardous: No
CAT#:0209-102-P105Size:100 µg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
TGF-β family members are key modulators of cell proliferation, differentiation, matrix synthesis, and apoptosis. As implied by their name, BMPs initiate, promote, and regulate the development, growth and remodeling of bone and cartilage. In addition to this role, BMPs are also involved in prenatal development and postnatal growth, remodeling and maintenance of a variety of other tissues and organs. BMP-7, also known as osteogenic protein-1 or OP-1, is a potent bone inducing agent, which in the presence of appropriate osteoconductive carrier (e.g. collagen sponge or synthetic hydroxyapatite) can be used in the treatment of bone defects. A bone-graft substitute, called OP-1TM implant, made of recombinant human BMP-7 associated with bovine bone-derived collagen, has recently been approved by the FDA as a device for treating critical-size bone fractures. The potential use of BMP-7 in dental reconstructive surgeries is currently under investigation. Recombinant human BMP-7 is a 28.8 kDa homodimeric glycoprotein consisting of two 116 amino acid subunits, which correspond to amino acid residues 316 to 431 of the full-length BMP-7 precursor.
Synonyms
BMP7; OP-1
NCBI Gene ID
655
UniProt
P18075
Accession Number
NP_001710.1
Accession Number mRNA
NM_001719.2
Chromosomal Location
20q13
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
CHO cells derived Recombinant Human BMP-8
Clone
Rabbit IgG
Applications
ELISA, WB
Purification Method
Antigen-affinity purified
Assay Protocol
Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.
Form
Lyophilized from PBS
Buffer
PBS
Reconstitution
Water
Storage Conditions
The lyophilized antibody is stable for at least 2 years from date of receipt at -20°C. The reconstituted antibody is stable for at least two weeks at 2-8°C. Frozen aliquots are stable for at least 6 months when stored at -20°C.
Host or Source
Rabbit

Related Products

CatalogName
100-405-L1000BMP-10
100-048-L250BMP-2
100-394-L100BMP-3
100-394-L1000BMP-3
100-326-L500BMP-4
100-326H-L1000BMP-4
M10-044-L100BMP-4
M10-044-L250BMP-4
200-001BMP-2
100-388BMP-5

Alternative Products

CatalogName
167769-01BMP-7, Recombinant, Human, aa1-139 (human BMP-7, BMP-7, BMP7, BMP 7, h-BMP-7, rh-BMP-7, recombinant human BMP-7, recombinant BMP-7, BMP) discontinued
Y00601-01BMP-7
MBS8575225-01BMP-7, Human
MBS494756-01BMP-7 ELISA
OAPA00163-5UGBMP-7 Antibody
sc-517294BMP-7 (6E5D12)
20R-1847BMP 7 antibody
OPPA02098-10UGBMP 7 Protein
sc-53917BMP-7 (4E7)
533647-01BMP-7 discontinued

Popular Products