Products for Research Use Only
RegisterLogin

BMP-4 Recombinant Protein

CAT: 0209-100-326CSize: 10 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0209-100-326CSize:10 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Bone morphogenetic proteins (BMPs) constitute a subfamily within the TGF-β superfamily of structurally related signaling proteins. Members of this superfamily are widely distributed throughout the body and are involved in diverse physiological processes during both pre- and postnatal life. Like BMP-7, BMP-4 is involved in the development and maintenance of bone and cartilage. Reduced expression of BMP-4 is associated with a number of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. Recombinant human BMP-4, expressed in HeLa cells, is a 31-36 kDa homodimeric glycoprotein.
CAS Number
9000-83-3
Synonyms
BMP4; ZYME; BMP2B; OFC11; BMP2B1; MCOPS6
NCBI Gene ID
652
UniProt
P12644
Accession Number
NP_001193
Accession Number mRNA
NM_001202
Gene Location
14q22-q23
Host
CHO
Origin Species
Human
Species Reactivity
Human, Mouse, Rat
Sequence
SPKHHSQRAR KKNKNCRRHS LYVDFSDVGW NDWIVAPPGY QAFYCHGDCP FPLADHLNST NHAI VQT LVN SVNSSIPKAC CVPTELSAIS MLYLDEYDKV VLKNYQEMVV EGCGCR.
Detection Range
The ED50, as calculated by Alkaline phosphatase activity induced in ATDC-5 cells is 15ng/ml corresponding to a specific activity which is 6.7 x 10^4 units/mg.
Purity
>95% by SDS-PAGE
Length
116
Form
Lyophilized
Buffer
2XS PBS + 6% EtOH
Molecular Weight
26,2 kDa
Shipping Conditions
Room Temperature

UniProtKB · P12644

Bone morphogenetic protein 4

BMP4_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P12644
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
BMP4
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
BMP-4
EC number
—
Processing
Precursor
Secondary accessions
Q9UM80
Protein keywords

Biological process

ChondrogenesisDifferentiationOsteogenesis

PTM

Cleavage on pair of basic residuesDisulfide bondGlycoproteinPhosphoprotein

Molecular function

CytokineDevelopmental proteinGrowth factor

Disease

Disease variantMicrophthalmia

Cellular component

Extracellular matrixSecreted

Technical term

Proteomics identificationReference proteome

Domain

Signal

Related Products

CatalogName
M10-044-L250BMP-4
M10-044-L100BMP-4
100-326H-L1000BMP-4
100-326-L500BMP-4
100-326H-L50BMP-4
100-326-L100BMP-4
101-M166BMP-4
101-M235BMP-4
M10-044-L500BMP-4
100-326C-L10BMP-4

Alternative Products

CatalogName
40-615-01BMP-4 Recombinant Protein
32-1082-10BMP 4 Recombinant Protein
TMPR-00001BMP-4 Protein, Human, Recombinant
PROTP21275Recombinant Murine BMP-4 Protein
TL-607-0050Recombinant Human BMP-4 Protein
ARP1347-01Recombinant Human BMP- 4 Protein
TMPY-06842-01BMP-4 Protein, Human, Recombinant (E399D)
314-BP-500/CFRecombinant Human BMP-4 Protein CF
BMP0904-500Recombinant human BMP-4 (monomer) protein
TMPH-01017-01BMP-4 Protein, Human, Recombinant (His)

Popular Products