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BMP-4 Recombinant Protein

CAT: 0209-100-326CSize: 10 µgDry Ice: NoHazardous: No
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CAT#:0209-100-326CSize:10 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Bone morphogenetic proteins (BMPs) constitute a subfamily within the TGF-β superfamily of structurally related signaling proteins. Members of this superfamily are widely distributed throughout the body and are involved in diverse physiological processes during both pre- and postnatal life. Like BMP-7, BMP-4 is involved in the development and maintenance of bone and cartilage. Reduced expression of BMP-4 is associated with a number of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. Recombinant human BMP-4, expressed in HeLa cells, is a 31-36 kDa homodimeric glycoprotein.
CAS Number
9000-83-3
Synonyms
BMP4; ZYME; BMP2B; OFC11; BMP2B1; MCOPS6
NCBI Gene ID
652
UniProt
P12644
Accession Number
NP_001193
Accession Number mRNA
NM_001202
Gene Location
14q22-q23
Host
CHO
Origin Species
Human
Species Reactivity
Human, Mouse, Rat
Sequence
SPKHHSQRAR KKNKNCRRHS LYVDFSDVGW NDWIVAPPGY QAFYCHGDCP FPLADHLNST NHAI VQT LVN SVNSSIPKAC CVPTELSAIS MLYLDEYDKV VLKNYQEMVV EGCGCR.
Detection Range
The ED50, as calculated by Alkaline phosphatase activity induced in ATDC-5 cells is 15ng/ml corresponding to a specific activity which is 6.7 x 10^4 units/mg.
Purity
>95% by SDS-PAGE
Length
116
Form
Lyophilized
Buffer
2XS PBS + 6% EtOH
Molecular Weight
26,2 kDa
Shipping Conditions
Room Temperature

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