Arginase 1

CAT: 0209-101-M136Size: 50 µgDry Ice: NoHazardous: No
CAT#:0209-101-M136Size:50 µg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Arginase-1 (ARG1) deficiency is a rare autosomal recessive disorder that affects the liver-based urea cycle, leading to impaired ureagenesis. This genetic disorder is caused by 40+ mutations found fairly uniformly spread throughout the ARG1 gene, resulting in partial or complete loss of enzyme function, which catalyzes the hydrolysis of arginine to ornithine and urea. ARG1-deficient patients exhibit hyperargininemia with spastic paraparesis, progressive neurological and intellectual impairment, persistent growth retardation, and infrequent episodes of hyperammonemia, a clinical pattern that differs strikingly from other urea cycle disorders.
Synonyms
Liver-type arginase, Type I arginase, ARG1
NCBI Gene ID
383
UniProt
P05089
Accession Number
NP_000036.2
Accession Number mRNA
NM_000045.3
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Recombinant human Arginase 1
Clone
(#41P23)
Applications
WB, FC, IP
Purification Method
Protein G chromatography
Assay Protocol
Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.
Host or Source
Mouse
Isotype
IgG2

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Alternative Products

CatalogName
545275Arginase
A3340-04BArginase, Liver Type (Arginase 1, Arginase-1, ARG1, Arginase Type I, MGC128755, Type I Arginase) discontinued
475522ARG1 (Arginase-1, Arginase, Liver)
139346ARG1 (Arginase-1, Liver-type Arginase, Type I Arginase)
475525ARG2 (Arginase II, Kidney-type Arginase, Non-hepatic Arginase)
139348ARG2 (Arginase-2, Mitochondrial, Kidney-type Arginase, Non-hepatic Arginase, Type II Arginase)
123477-FITCARG2 (Arginase-2, Mitochondrial, Kidney-type Arginase, Non-hepatic Arginase, Type II Arginase) (FITC)
123476-HRPARG2 (Arginase-2, Mitochondrial, Kidney-type Arginase, Non-hepatic Arginase, Type II Arginase) (HRP)

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