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ADAM-19

CAT: 0209-103-M302Size: 100 µgDry Ice: NoHazardous: No
CAT#:0209-103-M302Size:100 µg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ADAM-19 (a disintegrin and metalloprotease 19; also MADDAM and Meltrinβ) is a 95-100 kDa member of the M12B peptidase family of enzymes. It is expressed on multiple cell types including monocytes, fibroblasts, osteoblasts and dendritic cells. After cleavage of a signal sequence and prodomain, the ectodomain circulates in plasma bound to α2 Macroglobulin. ADAM19 cleaves at sequences present in myelin basic protein, insulin β chain, TNFα, TRANCE and SCF. Over amino acids (aa) 205-705, mouse ADAM19 shares 87% aa sequence identity with human ADAM19.
Synonyms
Adam19; M[b]; Mltnb; AL024287
NCBI Gene ID
11492
UniProt
O35674
Accession Number
NP_033746.1
Accession Number mRNA
NM_009616
Chromosomal Location
11 A5-B1.1; 11 20.0 cM
Reactivity
Anti-Mouse
Cross Reactivity
Mouse
Target Antigen
Recombinant protein of A Disintegrin and Metalloprotease-like Domain 19 ectodomain
Clone
(#11J23)
Applications
WB
Purification Method
Protein G chromatography
Assay Protocol
Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Bioactivity
WB: 1:500-1000.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Host or Source
Rat
Isotype
IgG2

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Alternative Products

CatalogName
251997ADAM 19 Antibody
A0859-37ADAM 19 (A Disintegrin And Metalloproteinase 19) (Biotin)
A0859-69ADAMTS19, ID (A Disintegrin And Metalloproteinase With Thrombospondin Motifs 19, ADAMTS-19, ADAM-TS 19, ADAM-TS19)
216115ADAM19 (ADAM-19, A Disintegrin and Metalloproteinase Domain 19)
MBS6461535-01ADAMTS19, ID (A Disintegrin And Metalloproteinase With Thrombospondin Motifs 19, ADAMTS-19, ADAM-TS 19, ADAM-TS19) (FITC)
MBS6461533-01ADAMTS19, ID (A Disintegrin And Metalloproteinase With Thrombospondin Motifs 19, ADAMTS-19, ADAM-TS 19, ADAM-TS19) (APC)
MBS6461534-01ADAMTS19, ID (A Disintegrin And Metalloproteinase With Thrombospondin Motifs 19, ADAMTS-19, ADAM-TS 19, ADAM-TS19) (Biotin)
MBS6461542-01ADAMTS19, ID (A Disintegrin And Metalloproteinase With Thrombospondin Motifs 19, ADAMTS-19, ADAM-TS 19, ADAM-TS19) (PE)
MBS6461532-01ADAMTS19, ID (A Disintegrin And Metalloproteinase With Thrombospondin Motifs 19, ADAMTS-19, ADAM-TS 19, ADAM-TS19) (AP)
A0859-69-FITCADAMTS19, ID (A Disintegrin And Metalloproteinase With Thrombospondin Motifs 19, ADAMTS-19, ADAM-TS 19, ADAM-TS19) (FITC) discontinued

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