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Nucleoside diphosphate kinase

CAT: 0804-HY-P2881Size: 500 UDry Ice: NoHazardous: No
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CAT#:0804-HY-P2881Size:500 U
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Description
Nucleoside diphosphate kinase (Nucleoside 5′-diphosphate kinase) belongs to the family of structurally and functionally conserved NDPK (Nucleotide diphosphate kinase) enzymes. Nucleoside diphosphate kinase catalyzes the reversible transfer of γ-phosphates between nucleoside di- (NDP) and triphosphates (NTP) through ping-pong bi-bi reaction kinetics. Nucleoside diphosphate kinase is the essential housekeeping proteins that produces CTP (cytidine triphosphate) for lipid syntheses, UTP (Uridine triphosphate) for polysaccharide syntheses, and GTP (guanosine triphosphate) for protein syntheses, signal transduction, and microtubules polymerization[1].
CAS Number
9026-51-1
Product Name Alternative
Nucleoside 5′-diphosphate kinase
UNSPSC
12352204
Target
Biochemical Assay Reagents
Type
Enzyme
Related Pathways
Others
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/nucleoside-diphosphate-kinase.html
Solubility
10 mM in DMSO
Smiles
[Nucleosidediphosphatekinase]
References & Citations
[1]Sengupta P, et al. Inosine 5'-diphosphate, a molecular decoy rescues Nucleoside diphosphate kinase from c-MYC G-Quadruplex unfolding. Biochim Biophys Acta Gen Subj. 2020 Sep;1864 (9) :129649.
Shipping Conditions
Room Temperature
Storage Conditions
Store at 4°C for 2 years
Scientific Category
Enzyme
Clinical Information
No Development Reported