CHAPS (hydrate)

• UNSPSC Description:

  CHAPS hydrate, a derivative of Cholic acid, is a zwitterionic detergent for solubilizing membrane proteins. CHAPS hydrate is used for stabilization of various protein-DNA complexes and can retain biochemical activity of proteins in solution[1][2].

• Target Antigen:

  Biochemical Assay Reagents

• Type:

  Biochemical Assay Reagents

• Related Pathways:

  Others

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/chaps-hydrate.html

• Solubility:

  DMSO : 10.87 mg/mL (ultrasonic;warming;heat to 60°C)

• Smiles:

  O[C@H]1[C@@]2([H])[C@@]3([H])[C@@]([C@@](CC3)([H])[C@H](C)CCC(NCCC[N+](C)(C)CCCS(=O)([O-])=O)=O)([C@H](C[C@]2([H])[C@@]4([C@](C[C@@H](CC4)O)([H])C1)C)O)C.O

• Molecular Weight:

  632.89

• References & Citations:

  [1]Kroflic A, et al. Thermodynamic characterization of 3-[(3-cholamidopropyl)-dimethylammonium]-1-propanesulfonate (CHAPS) micellization using isothermal titration calorimetry: temperature, salt, and pH dependence. Langmuir. 2012 Jul 17;28(28):10363-71.|[2]Menshikova I, et al. Nucleosomes structure and dynamics: effect of CHAPS. Int J Biochem Mol Biol. 2011;2(2):129-137.

• Shipping Conditions:

  Room Temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  331717-45-4