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2-Methylvaleric acid

CAT: 0804-HY-W010516-01Size: 10 gDry Ice: NoHazardous: No
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CAT#:0804-HY-W010516-01Size:10 g
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
2-Methylvaleric acid is a branched short-chain fatty acid (SCFA) produced by the metabolism of branched-chain amino acids by gut microbes. 2-Methylvaleric acid can be used as a potential biomarker for metabolic diseases such as type 2 diabetes, and its content is significantly reduced in the feces of diabetic mice. 2-Methylvaleric acid may regulate host energy metabolism and inflammatory response through G protein-coupled receptors (GPCRs) or histone deacetylase (HDAC) inhibition. 2-Methylvaleric acid can be used to study gut microbe-host interactions and metabolic diseases as a fecal biomarker[1][2].
CAS Number
97-61-0
Product Name Alternative
2-Methylpentanoic acid
UNSPSC
12352211
Hazard Statement
H227, H314
Target
Endogenous Metabolite
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/2-methylvaleric-acid.html
Purity
99.98
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CCCC(C)C(O)=O
Molecular Formula
C6H12O2
Molecular Weight
116.16
Precautions
H227, H314
References & Citations
[1]Menghan Li, et al. A sensitive method for the quantification of short-chain fatty acids by benzyl chloroformate derivatization combined with GC-MS. Analyst. 2020 Apr 7;145 (7) :2692-2700.|[2]StoneSá, et al. Phytochemistry and antimicrobial activity of Campomanesia adamantium. Revista Brasileira de Farmacognosia. Volume 28, Issue 3, May-June 2018, Pages 303-311
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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