DBCO-NHCO-S-S-NHS ester
CAT:
804-HY-133412-01
Size:
10 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
DBCO-NHCO-S-S-NHS ester
- UNSPSC Description: DBCO-NHCO-S-S-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. DBCO-NHCO-S-S-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
- Target Antigen: ADC Linker
- Type: ADC Related
- Related Pathways: Antibody-drug Conjugate/ADC Related
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/dbco-nhco-s-s-nhs-ester.html
- Smiles: O=C(N1C2=CC=CC=C2C#CC3=CC=CC=C3C1)CCNC(CCSSCCC(ON4C(CCC4=O)=O)=O)=O
- Molecular Weight: 565.66
- References & Citations: [1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.
- Shipping Conditions: Blue Ice