S-15535

• Description:

  S-15535 is a highly selective 5-HT1A receptor ligand. S-15535 is an antagonist of postsynaptic 5-HT1A receptors and an agonist of presynaptic 5-HT1A receptors. S-15535 can be used in research on psychiatric disorders, such as anti-anxiety[1].

• Product Name Alternative:

  WX-UK1; UKI-1C, BYK61359

• UNSPSC:

  12352005

• Hazard Statement:

  H302-H315-H319-H335

• Target:

  5-HT Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein; Neuronal Signaling

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/s-15535.html

• Purity:

  99.82

• Solubility:

  DMSO : 100 mg/mL (ultrasonic; warming; heat to 80°C)

• Smiles:

  N1(CCN(CC1)C2CC3=C(C2)C=CC=C3)C4=C5OCCOC5=CC=C4

• Molecular Formula:

  C21H24N2O2

• Molecular Weight:

  336.43

• Precautions:

  P261-P280-P302+P352

• References & Citations:

  [1]Millan MJ, et al. S 15535: a highly selective benzodioxopiperazine 5-HT1A receptor ligand which acts as an agonist and an antagonist at presynaptic and postsynaptic sites respectively. Eur J Pharmacol. 1993 Jan 5;230 (1) :99-102.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  Phase 2

• Isoform:

  5-HT1 Receptor

• CAS Number:

  [146998-34-7]