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1-A-N

CAT: 0804-HY-159675Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-159675Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
1-A-N is a lipid nanoparticle (LNP) used for in vivo delivery of siRNA. 1-A-N can regulate immune response by delivering siCD45 (siRNA targeting CD45) to T cells and silencing the CD45 gene[1].
UNSPSC
12352211
Target
Liposome
Type
Oligonucleotides
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/1-a-n.html
Smiles
CC/C=C\C/C=C\C/C=C\CCCCCCCC(OCC(COC(CC12C[C@H]3C[C@@H](C2)C[C@H](C3)C1)=O)COC(OCCCN4CCCC4)=O)=O
Molecular Formula
C42H67NO7
Molecular Weight
697.98
References & Citations
[1]Lokugamage M P, et al. Constrained nanoparticles deliver siRNA and sgRNA to T cells in vivo without targeting ligands[J]. Advanced Materials, 2019, 31 (41) : 1902251.
Shipping Conditions
Room temperature
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported

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